Meet Our researchers

Our dedicated team of researchers each with their own unique skillset

Inge R. Holtman

Inge R. Holtman

Assistant Professor – Rosalind Franklin Junior Group Leader

Studies how genetic variation influences susceptibility to brain diseases. Founder of the Netherlands Neurogenomics Database (NND).

i.r.holtman@umcg.nl
Alejandro Marmolejo Garza

Alejandro Marmolejo Garza

Postdoctoral Fellow

Focuses on brain organoid models for psychiatric disease and mitochondrial involvement in Alzheimer’s disease.

a.marmolejo.garza@umcg.nl
Shivam Kumar

Shivam Kumar

Postdoctoral Fellow

Works on machine learning for pathological imaging and predicting clinical traits from biomedical data.

s.kumar@umcg.nl
Nienke Mekkes

Nienke Mekkes

PhD Student

Researches brain disorders using cross-diagnostic approaches integrating multi-omics and clinical data.

n.j.mekkes@umcg.nl
Ruhi Soni

Ruhi Soni

Research Analyst

Focuses on biological signatures underlying psychiatric disorders using bioinformatics approaches.

r.soni@umcg.nl
Eric Hoekstra

Eric Hoekstra

Technician – Bioinformatician

Builds and maintains the NND infrastructure, computational pipelines, and data systems.

e.j.hoekstra@umcg.nl
Marysia Michalak

Marysia Michalak

Intern

I am working on establishing a robust CRISPRi system to downregulate the POLG gene in cerebral organoids. By inducing mitochondrial dysfunction, we aim to mimic aspects of cellular aging and generate a more physiologically relevant aged phenotype in this model.

m.a.michalak@umcg.nl
Emily Farrugia

Emily Farrugia

Intern

Benchmarking dissociation strategies for dorsal forebrain organoids to optimize single-cell resolution transcriptomics and examine how prenatal stressors alter neurodevelopment and neuropsychiatric disorder risk.

e.farrugia@umcg.nl
Sanne Jansen

Sanne Jansen

Intern

I am working with synthetic raw-medical files representing the NBB-cohort, applying Optical Character Recognition and de-identification tools to be able to extract key neuropathological features aiming to disentangle of the heterogeneity of neuropathological disease trajectories.

s.j.jansen@umcg.nl

Former members

  • Abel Koffeman
  • Yanneck Klenz
  • Tommaso Fortunato Asquini
  • Ekaterina Dagkesamanskaia
  • Maaike Brummer
  • Gwenny Leistra
  • Sander Bouwman
  • Bart Engels
  • Alyse de Boer
  • Henrike Vaartstra